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Generation of charge-reduced ions of membrane protein complexes for native ion mobility mass spectrometry studies

Recent advances in native mass spectrometry (MS) have enabled the elucidation of how small molecule binding to membrane proteins modulates their structure and function. The protein stabilizing osmolyte, Trimethylamine oxide (TMAO), exhibits attractive properties for native MS studies. Here, we repor...

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Detalhes bibliográficos
Publicado no:J Am Soc Mass Spectrom
Main Authors: Patrick, John W., Laganowsky, Arthur
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504596/
https://ncbi.nlm.nih.gov/pubmed/30887461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-019-02187-6
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