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Generation of charge-reduced ions of membrane protein complexes for native ion mobility mass spectrometry studies

Recent advances in native mass spectrometry (MS) have enabled the elucidation of how small molecule binding to membrane proteins modulates their structure and function. The protein stabilizing osmolyte, Trimethylamine oxide (TMAO), exhibits attractive properties for native MS studies. Here, we repor...

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Bibliografiske detaljer
Udgivet i:J Am Soc Mass Spectrom
Main Authors: Patrick, John W., Laganowsky, Arthur
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504596/
https://ncbi.nlm.nih.gov/pubmed/30887461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-019-02187-6
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