The activation state of CD4 T cells alters cellular peptidase activities and HIV antigen processing and MHC-I presentation in a sequence-dependent manner

CD4 T cell activation is critical to the initiation of adaptive immunity. CD4 T cells are also the main targets of HIV infection and their activation status contributes to the maintenance and outcome of infection. While the role of activation in the differentiation and proliferation of CD4 T cells i...

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Pubblicato in:J Immunol
Autori principali: Boucau, Julie, Madouasse, Julien, Kourjian, Georgio, Carlin, Christopher S., Wambua, Daniel, Berberich, Matthew J., Le Gall, Sylvie
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504579/
https://ncbi.nlm.nih.gov/pubmed/30936293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700950
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