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ST2/MyD88 deficiency protects mice against aGVHD and spares T-regulatory cells
Acute graft-versus-host disease (aGVHD) hinders the efficacy of allogeneic hematopoietic cell transplantation (HCT). Plasma levels of soluble ST2 (sST2) are elevated in human and murine aGVHD and correlated to type 1 T cells response. Membrane-bound ST2 (ST2) signals through the adapter protein MyD8...
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| 出版年: | J Immunol |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6504559/ https://ncbi.nlm.nih.gov/pubmed/30979817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800447 |
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