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The impact of Megf10/Drpr gain-of-function on muscle development in Drosophila

Recessive mutations in multiple EGF-like domains 10 (MEGF10) underlie a rare congenital muscle disease known as MEGF10 myopathy. MEGF10 and its Drosophila homolog Draper (Drpr) are transmembrane receptors expressed in muscle and glia. Drpr deficiency is known to result in muscle abnormalities in fli...

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Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Draper, Isabelle, Saha, Madhurima, Stonebreaker, Hannah, Salomon, Robert N., Matin, Bahar, Kang, Peter B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504253/
https://ncbi.nlm.nih.gov/pubmed/30802937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13348
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