Silencing of drpr Leads to Muscle and Brain Degeneration in Adult Drosophila

Mutations in the gene encoding the single transmembrane receptor multiple epidermal growth factor-like domain 10 (MEGF10) cause an autosomal recessive congenital muscle disease in humans. Although mammalian MEGF10 is expressed in the central nervous system as well as in skeletal muscle, patients car...

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Detalles Bibliográficos
Main Authors: Draper, Isabelle, Mahoney, Lane J., Mitsuhashi, Satomi, Pacak, Christina A., Salomon, Robert N., Kang, Peter B.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2014
Assuntos:
Regular Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188861/
https://ncbi.nlm.nih.gov/pubmed/25111228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.06.018
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