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Silencing of drpr Leads to Muscle and Brain Degeneration in Adult Drosophila

Mutations in the gene encoding the single transmembrane receptor multiple epidermal growth factor-like domain 10 (MEGF10) cause an autosomal recessive congenital muscle disease in humans. Although mammalian MEGF10 is expressed in the central nervous system as well as in skeletal muscle, patients car...

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Detalhes bibliográficos
Main Authors: Draper, Isabelle, Mahoney, Lane J., Mitsuhashi, Satomi, Pacak, Christina A., Salomon, Robert N., Kang, Peter B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188861/
https://ncbi.nlm.nih.gov/pubmed/25111228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.06.018
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