IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to Staphylococcus aureus

Methicillin-resistant Staphylococcus aureus (MRSA) is a major hospital- and community-acquired pathogen, but the mechanisms underlying host-defense to MRSA remain poorly understood. Here, we investigated the role of IL-21 in this process. When administered intra-tracheally into wild-type mice, IL-21...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Spolski, Rosanne, West, Erin E, Li, Peng, Veenbergen, Sharon, Yung, Sunny, Kazemian, Majid, Oh, Jangsuk, Yu, Zu-Xi, Freeman, Alexandra F, Holland, Stephen M, Murphy, Philip M, Leonard, Warren J
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2019
Matèries:
Immunology and Inflammation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504231/
https://ncbi.nlm.nih.gov/pubmed/30969166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.45501
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