Cell–cell fusion induced by reovirus FAST proteins enhances replication and pathogenicity of non-enveloped dsRNA viruses

Fusogenic reoviruses encode fusion-associated small transmembrane (FAST) protein, which induces cell–cell fusion. FAST protein is the only known fusogenic protein in non-enveloped viruses, and its role in virus replication is not yet known. We generated replication-competent, FAST protein-deficient...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Kanai, Yuta, Kawagishi, Takahiro, Sakai, Yusuke, Nouda, Ryotaro, Shimojima, Masayuki, Saijo, Masayuki, Matsuura, Yoshiharu, Kobayashi, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504114/
https://ncbi.nlm.nih.gov/pubmed/31022290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007675
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