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An in vivo half-life extended prolactin receptor antagonist can prevent STAT5 phosphorylation

Increasing evidence suggests that signaling through the prolactin/prolactin receptor axis is important for stimulation the growth of many cancers including glioblastoma multiforme, breast and ovarian carcinoma. Efficient inhibitors of signaling have previously been developed but their applicability...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Yu, Shengze, Alkharusi, Amira, Norstedt, Gunnar, Gräslund, Torbjörn
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504076/
https://ncbi.nlm.nih.gov/pubmed/31063493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215831
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