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An in vivo half-life extended prolactin receptor antagonist can prevent STAT5 phosphorylation

Increasing evidence suggests that signaling through the prolactin/prolactin receptor axis is important for stimulation the growth of many cancers including glioblastoma multiforme, breast and ovarian carcinoma. Efficient inhibitors of signaling have previously been developed but their applicability...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yu, Shengze, Alkharusi, Amira, Norstedt, Gunnar, Gräslund, Torbjörn
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504076/
https://ncbi.nlm.nih.gov/pubmed/31063493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215831
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