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Wnt signaling mediates new nephron formation during zebrafish kidney regeneration

Zebrafish kidneys use resident kidney stem cells to replace damaged tubules with new nephrons: the filtration units of the kidney. What stimulates kidney progenitor cells to form new nephrons is not known. Here, we show that wnt9a and wnt9b are induced in the injured kidney at sites where frizzled9b...

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Publicat a:Development
Autors principals: Kamei, Caramai N., Gallegos, Thomas F., Liu, Yan, Hukriede, Neil, Drummond, Iain A.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503981/
https://ncbi.nlm.nih.gov/pubmed/31036548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.168294
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