Identification of adult nephron progenitors capable of kidney regeneration in zebrafish

Loss of kidney function underlies many renal diseases(1). Mammals can partly repair their nephrons (the functional units of the kidney), but cannot form new ones(2,3). By contrast, fish add nephrons throughout their lifespan and regenerate nephrons de novo after injury(4,5), providing a model for un...

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Hauptverfasser: Diep, Cuong Q., Ma, Dongdong, Deo, Rahul C., Holm, Teresa M., Naylor, Richard W., Arora, Natasha, Wingert, Rebecca A., Bollig, Frank, Djordjevic, Gordana, Lichman, Benjamin, Zhu, Hao, Ikenaga, Takanori, Ono, Fumihito, Englert, Christoph, Cowan, Chad A., Hukriede, Neil A., Handin, Robert I., Davidson, Alan J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170921/
https://ncbi.nlm.nih.gov/pubmed/21270795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09669
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