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A Modified Acetylcholine Receptor δ-Subunit Enables a Null Mutant to Survive Beyond Sexual Maturation

The contraction of skeletal muscle is dependent on synaptic transmission through acetylcholine receptors (AChRs) at the neuromuscular junction (NMJ). The lack of an AChR subunit causes a fetal akinesia in humans, leading to death in the first trimester and characteristic features of Fetal Akinesia D...

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Bibliografiska uppgifter
Huvudupphovsmän: Epley, Kimberly E., Urban, Jason M., Ikenaga, Takanori, Ono, Fumihito
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679261/
https://ncbi.nlm.nih.gov/pubmed/19052214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2814-08.2008
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