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Fluorescent peptide displacement as a general assay for screening small molecule libraries against RNA.

A prominent hurdle in developing small molecule probes against RNA is the relative scarcity of general screening methods. In this study, we demonstrate the application of a fluorescent peptide displacement assay to screen small molecule probes against four different RNA targets. The designed experim...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Patwardhan, Neeraj N., Cai, Zhengguo, Newson, Colby N., Hargrove, Amanda E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503966/
https://ncbi.nlm.nih.gov/pubmed/30468226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ob02467g
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