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Understanding the Contributions of Conformational Changes, Thermodynamics, and Kinetics of RNA–Small Molecule Interactions

The implication of RNA in multiple cellular processes beyond protein coding has revitalized interest in the development of small molecules for therapeutically targeting RNA and for further probing its cellular biology. However, the process of rationally designing such small molecule probes is hamper...

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Pubblicato in:ACS Chem Biol
Autori principali: Juru, Aline Umuhire, Patwardhan, Neeraj N., Hargrove, Amanda E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525067/
https://ncbi.nlm.nih.gov/pubmed/31042354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00945
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