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Understanding the Contributions of Conformational Changes, Thermodynamics, and Kinetics of RNA–Small Molecule Interactions

The implication of RNA in multiple cellular processes beyond protein coding has revitalized interest in the development of small molecules for therapeutically targeting RNA and for further probing its cellular biology. However, the process of rationally designing such small molecule probes is hamper...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Juru, Aline Umuhire, Patwardhan, Neeraj N., Hargrove, Amanda E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525067/
https://ncbi.nlm.nih.gov/pubmed/31042354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00945
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