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A Malaria Transmission-Blocking (+)-Usnic Acid Derivative Prevents Plasmodium Zygote-to-Ookinete Maturation in the Mosquito Midgut

The evolution of drug resistance is a recurrent problem that has plagued efforts to treat and control malaria. Recent emergence of artemisinin resistance in Southeast Asia underscores the need to develop novel antimalarials and identify new targetable pathways in Plasmodium parasites. Transmission-b...

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Vydáno v:ACS Chem Biol
Hlavní autoři: Pastrana-Mena, Rebecca, Mathias, Derrick K., Delves, Michael, Rajaram, Krithika, King, Jonas G., Yee, Rebecca, Trucchi, Beatrice, Verotta, Luisella, Dinglasan, Rhoel R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503959/
https://ncbi.nlm.nih.gov/pubmed/27978709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00902
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