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PML-Nuclear Bodies Regulate the Stability of the Fusion Protein Dendra2-Nrf2 in the Nucleus

BACKGROUND/AIMS: Nuclear factor erythroid 2-related factor 2 (Nrf2) is a basic leucine-zipper transcription factor essential for cellular responses to oxidative stress. Degradation of Nrf2 in the cytoplasm, mediated by Keap1-Cullin3/RING box1 (Cul3-Rbx1) E3 ubiquitin ligase and the proteasome, is co...

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Publicat a:Cell Physiol Biochem
Autors principals: Burroughs, Andrea Flores, Eluhu, Sylvia, Whalen, Diva, Goodwin, J. Shawn, Sakwe, Amos M., Arinze, Ifeanyi J.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503657/
https://ncbi.nlm.nih.gov/pubmed/29807365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000490033
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