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Mechanisms of decreased cholinergic arousal in focal seizures: in vivo whole-cell recordings from the pedunculopontine tegmental nucleus

Focal limbic seizures often impair consciousness/awareness with major negative impact on quality of life. Recent work has shown that limbic seizures depress brainstem arousal systems, including reduced action potential firing in a key node: cholinergic neurons of the pedunculopontine tegmental nucle...

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Detalhes bibliográficos
Publicado no:Exp Neurol
Main Authors: Andrews, John P., Yue, Zongwei, Hwan Ryu, Jun, Neske, Garrett, McCormick, David A., Blumenfeld, Hal
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503533/
https://ncbi.nlm.nih.gov/pubmed/30543800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2018.11.008
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