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Prenatal NAP+SAL Prevents Developmental Delay in Down Syndrome through affects on NMDA and GABA receptors

OBJECTIVE: Down Syndrome affects 1/800 infants. Prenatal NAP+SAL prevents developmental delay in Ts65Dn mice. We investigated if this finding involves NMDA and GABA receptor subunits. STUDY DESIGN: Pregnant Ts65Dn mice were treated with placebo or NAP+SAL on gestational days 8-12. After developmenta...

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Detalhes bibliográficos
Publicado no:Am J Obstet Gynecol
Main Authors: VINK, Joy, INCERTI, Maddelena, TOSO, Laura, ROBERSON, Robin, ABEBE, Daniel, SPONG, Catherine Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503529/
https://ncbi.nlm.nih.gov/pubmed/19327737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2009.01.052
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