Increased MCL-1 expression predicts poor prognosis and disease recurrence in acute myeloid leukemia

Background: Altered expression of the BCL-2 family member MCL-1 has been linked to the progression and outcome of various malignancies. Recently, MCL-1 inhibitor S63845 was reported to kill MCL-1-dependent cancer cells and has potential value in clinical application. Purpose: Herein, we reported MCL...

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Veröffentlicht in:Onco Targets Ther
Hauptverfasser: Li, Xi-xi, Zhou, Jing-dong, Wen, Xiang-mei, Zhang, Ting-juan, Wu, De-hong, Deng, Zhao-qun, Zhang, Zhi-hui, Lian, Xin-yue, He, Pin-fang, Yao, Xin-yu, Lin, Jiang, Qian, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2019
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503339/
https://ncbi.nlm.nih.gov/pubmed/31118680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S194549
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