Hypermethylation of secreted frizzled-related proteins predicts poor prognosis in non-M3 acute myeloid leukemia

OBJECTIVE: Secreted frizzled-related proteins (SFRPs) as Wnt signaling antagonists have been found to be dysregulated by promoter hypermethylation in several cancers including acute myeloid leukemia (AML). This study aimed to investigate the methylated status of SFRPs promoter region and its clinica...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Onco Targets Ther
Κύριοι συγγραφείς: Guo, Hong, Zhang, Ting-juan, Wen, Xiang-mei, Zhou, Jing-dong, Ma, Ji-chun, An, Cui, Zhang, Wei, Xu, Zi-jun, Lin, Jiang, Qian, Jun
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Dove Medical Press 2017
Θέματα:
Original Research
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530859/
https://ncbi.nlm.nih.gov/pubmed/28790854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S136502
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