Hypermethylation of secreted frizzled-related proteins predicts poor prognosis in non-M3 acute myeloid leukemia

OBJECTIVE: Secreted frizzled-related proteins (SFRPs) as Wnt signaling antagonists have been found to be dysregulated by promoter hypermethylation in several cancers including acute myeloid leukemia (AML). This study aimed to investigate the methylated status of SFRPs promoter region and its clinica...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Onco Targets Ther
Prif Awduron: Guo, Hong, Zhang, Ting-juan, Wen, Xiang-mei, Zhou, Jing-dong, Ma, Ji-chun, An, Cui, Zhang, Wei, Xu, Zi-jun, Lin, Jiang, Qian, Jun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Dove Medical Press 2017
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530859/
https://ncbi.nlm.nih.gov/pubmed/28790854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S136502
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