Hypermethylation of secreted frizzled-related proteins predicts poor prognosis in non-M3 acute myeloid leukemia

OBJECTIVE: Secreted frizzled-related proteins (SFRPs) as Wnt signaling antagonists have been found to be dysregulated by promoter hypermethylation in several cancers including acute myeloid leukemia (AML). This study aimed to investigate the methylated status of SFRPs promoter region and its clinica...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Guo, Hong, Zhang, Ting-juan, Wen, Xiang-mei, Zhou, Jing-dong, Ma, Ji-chun, An, Cui, Zhang, Wei, Xu, Zi-jun, Lin, Jiang, Qian, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530859/
https://ncbi.nlm.nih.gov/pubmed/28790854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S136502
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