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Local and systemic delivery of mRNA encoding survivin-T34A by lipoplex for efficient colon cancer gene therapy

Background: In vitro transcribed (IVT) mRNA has been applied as an alternative therapeutic molecule to plasmid DNA in the field of cancer therapy and biomedical research studies. mRNA-based therapy has demonstrated several advantages over its DNA counterparts. However, its further therapeutic applic...

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Detalles Bibliográficos
Publicado en:Int J Nanomedicine
Main Authors: Zhang, Xueyan, Men, Ke, Zhang, Yuanfa, Zhang, Rui, Yang, Li, Duan, Xingmei
Formato: Artigo
Idioma:Inglês
Publicado: Dove 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503337/
https://ncbi.nlm.nih.gov/pubmed/31118608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S198747
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