Efficient inhibition of ovarian cancer by degradable nanoparticle-delivered survivin T34A gene

Gene therapy has promising applications in ovarian cancer therapy. Blocking the function of the survivin protein could lead to the growth inhibition of cancer cells. Herein, we used degradable heparin–polyethyleneimine (HPEI) nanoparticles to deliver a dominant-negative human survivin T34A (hs-T34A)...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Luo, Li, Du, Ting, Zhang, Jiumeng, Zhao, Wei, Cheng, Hao, Yang, Yuping, Wu, Yujiao, Wang, Chunmei, Men, Ke, Gou, Maling
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745847/
https://ncbi.nlm.nih.gov/pubmed/26893558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S93496
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