Enhanced immunosuppressive effects of 3,5-bis[4(diethoxymethyl)benzylidene]-1-methyl-piperidin-4-one, an α, β-unsaturated carbonyl-based compound as PLGA-b-PEG nanoparticles

Background: 3,5-Bis[4-(diethoxymethyl)benzylidene]-1-methyl-piperidin-4-one (BBP), a novel synthetic curcumin analogue has been revealed to possess strong in vitro and in vivo immunosuppressive effects. Purpose: The aim of present study was to prepare and characterize BBP-encapsulated polylactic-co-...

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Bibliographic Details
Published in:Drug Des Devel Ther
Main Authors: Arshad, Laiba, Jantan, Ibrahim, Bukhari, Syed Nasir Abbas
Format: Artigo
Language:Inglês
Published: Dove 2019
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503188/
https://ncbi.nlm.nih.gov/pubmed/31118577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S185191
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