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Exome sequencing in 51 early onset non‐familial CRC cases

BACKGROUND: Colorectal cancer (CRC) cases with an age of onset <40 years suggests a germline genetic cause. In total, 51 simplex cases were included to test the hypothesis of CRC as a mendelian trait caused by either heterozygous autosomal dominant or bi‐allelic autosomal recessive pathogenic var...

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Detalhes bibliográficos
Publicado no:Mol Genet Genomic Med
Main Authors: Thutkawkorapin, Jessada, Lindblom, Annika, Tham, Emma
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503031/
https://ncbi.nlm.nih.gov/pubmed/30809968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.605
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