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Exome sequencing in 51 early onset non‐familial CRC cases

BACKGROUND: Colorectal cancer (CRC) cases with an age of onset <40 years suggests a germline genetic cause. In total, 51 simplex cases were included to test the hypothesis of CRC as a mendelian trait caused by either heterozygous autosomal dominant or bi‐allelic autosomal recessive pathogenic var...

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Bibliografski detalji
Izdano u:Mol Genet Genomic Med
Glavni autori: Thutkawkorapin, Jessada, Lindblom, Annika, Tham, Emma
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503031/
https://ncbi.nlm.nih.gov/pubmed/30809968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.605
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