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Sodium butyrate and panobinostat induce apoptosis of chronic myeloid leukemia cells via multiple pathways

PURPOSE: Histone deacetylase inhibitor (HDACI) is a novel therapeutic option for cancer. However, the effects of HDACIs on chronic myeloid leukemia (CML) and the underlying mechanisms are still unknown. The aim of this study was to investigate the effect and the mechanism‐of‐action of two HDACI memb...

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Bibliografiske detaljer
Udgivet i:Mol Genet Genomic Med
Main Authors: Jia, Xiaoyuan, Zheng, Yinsuo, Guo, Yanzi, Chen, Kan
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503025/
https://ncbi.nlm.nih.gov/pubmed/30891950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.613
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