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Sodium butyrate and panobinostat induce apoptosis of chronic myeloid leukemia cells via multiple pathways

PURPOSE: Histone deacetylase inhibitor (HDACI) is a novel therapeutic option for cancer. However, the effects of HDACIs on chronic myeloid leukemia (CML) and the underlying mechanisms are still unknown. The aim of this study was to investigate the effect and the mechanism‐of‐action of two HDACI memb...

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Detalhes bibliográficos
Publicado no:Mol Genet Genomic Med
Main Authors: Jia, Xiaoyuan, Zheng, Yinsuo, Guo, Yanzi, Chen, Kan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503025/
https://ncbi.nlm.nih.gov/pubmed/30891950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.613
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