Caricamento...
The role of membrane excitability in pancreatic β-cell glucotoxicity
Persistent hyperglycemia is causally associated with pancreatic β-cell dysfunction and loss of pancreatic insulin. Glucose normally enhances β-cell excitability through inhibition of K(ATP) channels, opening of voltage-dependent calcium channels, increased [Ca(2+)](i), which triggers insulin secreti...
Salvato in:
| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6502887/ https://ncbi.nlm.nih.gov/pubmed/31061431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43452-8 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|