Functional high-throughput screening reveals miR-323a-5p and miR-342-5p as new tumor-suppressive microRNA for neuroblastoma

Current therapies for most non-infectious diseases are directed at or affect functionality of the human translated genome, barely 2% of all genetic information. By contrast, the therapeutic potential of targeting the transcriptome, ~ 70% of the genome, remains largely unexplored. RNA therapeutics is...

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Dettagli Bibliografici
Pubblicato in:Cell Mol Life Sci
Autori principali: Soriano, Aroa, Masanas, Marc, Boloix, Ariadna, Masiá, Núria, París-Coderch, Laia, Piskareva, Olga, Jiménez, Carlos, Henrich, Kai-Oliver, Roma, Josep, Westermann, Frank, Stallings, Raymond L., Sábado, Constantino, de Toledo, Josep Sánchez, Santamaria, Anna, Gallego, Soledad, Segura, Miguel F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6502783/
https://ncbi.nlm.nih.gov/pubmed/30770954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-019-03041-4
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