Deficiency of mouse mast cell protease 4 mitigates cardiac dysfunctions in mice after myocardium infarction

Mouse mast cell protease-4 (mMCP4) is a chymase that has been implicated in cardiovascular diseases, including myocardial infarction (MI). This study tested a direct role of mMCP4 in mouse post-MI cardiac dysfunction and myocardial remodeling. Immunoblot and immunofluorescent double staining demonst...

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Veröffentlicht in:Biochim Biophys Acta Mol Basis Dis
Hauptverfasser: Wang, Yunzhe, Liu, Cong-Lin, Fang, Wenqian, Zhang, Xian, Yang, Chongzhe, Li, Jie, Liu, Jing, Sukhova, Galina K., Gurish, Michael F., Libby, Peter, Shi, Guo-Ping, Zhang, Jinying
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6502670/
https://ncbi.nlm.nih.gov/pubmed/30639224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2019.01.011
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