Fenofibrate-Loaded Biodegradable Nanoparticles for the Treatment of Experimental Diabetic Retinopathy and Neovascular Age-Related Macular Degeneration

Fenofibrate is a peroxisome proliferator-activated receptor α (PPARα) agonist and has been shown to have therapeutic effects on diabetic retinopathy (DR). However, the effects of fenofibrate through systemic administration are not as potent as desired due to inefficient drug delivery to the retina....

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Bibliografiske detaljer
Udgivet i:Mol Pharm
Main Authors: Qiu, Fangfang, Meng, Tuo, Chen, Qian, Zhou, Kelu, Shao, Yan, Matlock, Greg, Ma, Xiang, Wu, Wenjing, Du, Yanhong, Wang, Xiang, Deng, Guotao, Ma, Jian-xing, Xu, Qingguo
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6502649/
https://ncbi.nlm.nih.gov/pubmed/30912953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.8b01319
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