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Fenofibrate-Loaded Biodegradable Nanoparticles for the Treatment of Experimental Diabetic Retinopathy and Neovascular Age-Related Macular Degeneration

Fenofibrate is a peroxisome proliferator-activated receptor α (PPARα) agonist and has been shown to have therapeutic effects on diabetic retinopathy (DR). However, the effects of fenofibrate through systemic administration are not as potent as desired due to inefficient drug delivery to the retina....

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Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: Qiu, Fangfang, Meng, Tuo, Chen, Qian, Zhou, Kelu, Shao, Yan, Matlock, Greg, Ma, Xiang, Wu, Wenjing, Du, Yanhong, Wang, Xiang, Deng, Guotao, Ma, Jian-xing, Xu, Qingguo
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6502649/
https://ncbi.nlm.nih.gov/pubmed/30912953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.8b01319
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