Cardiomyocyte dimethylarginine dimethylaminohydrolase-1 (DDAH1) plays an important role in attenuating ventricular hypertrophy and dysfunction

BACKGROUND: Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthases that limits nitric oxide bioavailability. Dimethylarginine dimethylaminohydrolase-1 (DDAH1) exerts a critical role for ADMA degradation and plays an important role in NO signaling. In the heart, DDAH1...

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Pubblicato in:Basic Res Cardiol
Autori principali: Xu, Xin, Zhang, Ping, Kwak, Dongmin, Fassett, John, Yue, Wenhui, Atzler, Dorothee, Hu, Xinli, Liu, Xiaohong, Wang, Huan, Lu, Zhongbing, Guo, Haipeng, Schwedhelm, Edzard, Böger, Rainer H., Chen, Peijie, Chen, Yingjie
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6502637/
https://ncbi.nlm.nih.gov/pubmed/28819685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-017-0644-z
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