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Intratumor DNA methylation heterogeneity in glioblastoma: implications for DNA methylation-based classification
BACKGROUND: A feature of glioblastoma (GBM) is cellular and molecular heterogeneity, both within and between tumors. This variability causes a risk for sampling bias and potential tumor escape from future targeted therapy. Heterogeneous intratumor gene expression in GBM is well documented, but littl...
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| Publié dans: | Neuro Oncol |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6502500/ https://ncbi.nlm.nih.gov/pubmed/30668814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz011 |
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