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Intratumor DNA methylation heterogeneity in glioblastoma: implications for DNA methylation-based classification

BACKGROUND: A feature of glioblastoma (GBM) is cellular and molecular heterogeneity, both within and between tumors. This variability causes a risk for sampling bias and potential tumor escape from future targeted therapy. Heterogeneous intratumor gene expression in GBM is well documented, but littl...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Neuro Oncol
Egile Nagusiak: Wenger, Anna, Ferreyra Vega, Sandra, Kling, Teresia, Bontell, Thomas Olsson, Jakola, Asgeir Store, Carén, Helena
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6502500/
https://ncbi.nlm.nih.gov/pubmed/30668814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz011
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