The arginine sensing and transport binding sites are distinct in the human pathogen Leishmania

The intracellular protozoan parasite Leishmania donovani causes human visceral leishmaniasis. Intracellular L. donovani that proliferate inside macrophage phagolysosomes compete with the host for arginine, creating a situation that endangers parasite survival. Parasites have a sensor that upon argin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Negl Trop Dis
Prif Awduron: Pawar, Harsh, Puri, Madhu, Fischer Weinberger, Renana, Madhubala, Rentala, Zilberstein, Dan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2019
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6502434/
https://ncbi.nlm.nih.gov/pubmed/31017889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007304
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