Single-dose Ag85B-ESAT6–loaded poly(lactic-co-glycolic acid) nanoparticles confer protective immunity against tuberculosis

BACKGROUND: Bacillus Calmette–Guérin, the attenuated strain of Mycobacterium bovis, remains the only available vaccine against tuberculosis (TB). However, its ineffectiveness in adults against pulmonary TB and varied protective efficacy (0–80%) speak to an urgent need for the development of an impro...

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Bibliografiske detaljer
Udgivet i:Int J Nanomedicine
Main Authors: Malik, Anshu, Gupta, Manish, Mani, Rajesh, Bhatnagar, Rakesh
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2019
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6501725/
https://ncbi.nlm.nih.gov/pubmed/31118627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S172391
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