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Single-dose Ag85B-ESAT6–loaded poly(lactic-co-glycolic acid) nanoparticles confer protective immunity against tuberculosis
BACKGROUND: Bacillus Calmette–Guérin, the attenuated strain of Mycobacterium bovis, remains the only available vaccine against tuberculosis (TB). However, its ineffectiveness in adults against pulmonary TB and varied protective efficacy (0–80%) speak to an urgent need for the development of an impro...
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| Publicado no: | Int J Nanomedicine |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6501725/ https://ncbi.nlm.nih.gov/pubmed/31118627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S172391 |
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