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Leukocyte Heparanase: A Double-Edged Sword in Tumor Progression

Heparanase is a β-D-endoglucuronidase that cleaves heparan sulfate, a complex glycosaminoglycan found ubiquitously throughout mammalian cells and tissues. Heparanase has been strongly associated with important pathological processes including inflammatory disease and tumor metastasis, through its ab...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Mayfosh, Alyce J., Baschuk, Nikola, Hulett, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6501466/
https://ncbi.nlm.nih.gov/pubmed/31110966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00331
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