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Epstein–Barr virus nuclear antigen 1 activates transcription from episomal but not integrated DNA and does not alter lymphocyte growth

By binding to a cis-acting element (oriP) in the Epstein–Barr virus (EBV) genome, EBV nuclear antigen 1 (EBNA1) enables persistence and enhances transcription from EBV episomes. To investigate whether EBNA1 also directly affects cell gene transcription, we conditionally expressed a Flag-tagged domin...

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Detalhes bibliográficos
Main Authors: Kang, Myung-Soo, Hung, Siu Chun, Kieff, Elliott
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC65012/
https://ncbi.nlm.nih.gov/pubmed/11734622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.211556598
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