CD33 (Siglec-3) Inhibitory Function: Role in the NKG2D/DAP10 Activating Pathway

CD33 (siglec-3), a well-known target in leukemia therapy, is an inhibitory sialoadhesin expressed in human leukocytes of the myeloid lineage and some lymphoid subsets, including NK cells. It may constitute a control mechanism of the innate immune system; nevertheless, its role as an inhibitory recep...

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Udgivet i:J Immunol Res
Main Authors: Hernández-Caselles, Trinidad, Miguel, Rubén Corral-San, Ruiz-Alcaraz, Antonio José, García-Peñarrubia, Pilar
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6501159/
https://ncbi.nlm.nih.gov/pubmed/31143782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/6032141
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