Retinoic acid‐induced autoantigen‐specific type 1 regulatory T cells suppress autoimmunity

Regulatory T (Treg) cells help to maintain tolerance and prevent the development of autoimmune diseases. Retinoic acid (RA) can promote peripheral conversion of naïve T cells into Foxp3(+) Treg cells. Here, we show that RA can act as an adjuvant to induce antigen‐specific type 1 Treg (Tr1) cells, wh...

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Dettagli Bibliografici
Pubblicato in:EMBO Rep
Autori principali: Raverdeau, Mathilde, Christofi, Maria, Malara, Anna, Wilk, Mieszko M, Misiak, Alicja, Kuffova, Lucia, Yu, Tian, McGinley, Aoife M, Quinn, Shauna M, Massilamany, Chandirasegaran, Reddy, Jay, Forrester, John V, Mills, Kingston HG
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
Soggetti:
Scientific Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500997/
https://ncbi.nlm.nih.gov/pubmed/30894405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201847121
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