Retinoic acid expression associates with enhanced IL-22 production by γδ T cells and innate lymphoid cells and attenuation of intestinal inflammation

Retinoic acid (RA), a vitamin A metabolite, modulates mucosal T helper cell responses. Here we examined the role of RA in regulating IL-22 production by γδ T cells and innate lymphoid cells in intestinal inflammation. RA significantly enhanced IL-22 production by γδ T cells stimulated in vitro with...

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Detalhes bibliográficos
Main Authors: Mielke, Lisa A., Jones, Sarah A., Raverdeau, Mathilde, Higgs, Rowan, Stefanska, Anna, Groom, Joanna R., Misiak, Alicja, Dungan, Lara S., Sutton, Caroline E., Streubel, Gundula, Bracken, Adrian P., Mills, Kingston H.G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674702/
https://ncbi.nlm.nih.gov/pubmed/23690441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121588
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