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Hypoxia‐inducible factor‐1α and nuclear factor‐κB play important roles in regulating programmed cell death ligand 1 expression by epidermal growth factor receptor mutants in non‐small‐cell lung cancer cells

Some driver gene mutations, including epidermal growth factor receptor (EGFR), have been reported to be involved in expression regulation of the immunosuppressive checkpoint protein programmed cell death ligand 1 (PD‐L1), but the underlying mechanism remains obscure. We investigated the potential ro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Sci
Hauptverfasser: Guo, Rong, Li, Yong, Wang, Zhijie, Bai, Hua, Duan, Jianchun, Wang, Shuhang, Wang, Lvhua, Wang, Jie
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500984/
https://ncbi.nlm.nih.gov/pubmed/30844110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13989
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