Mutation spectrum of germline cancer susceptibility genes among unselected Chinese colorectal cancer patients

Background: Genetic factors play an important role in colorectal cancer (CRC) risk, yet the prevalence and spectrum of germline cancer susceptibility gene mutations among unselected Chinese CRC patients is largely undetermined. Methods: We performed next-generation sequencing with a 73-genes panel a...

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Dades bibliogràfiques
Publicat a:Cancer Manag Res
Autors principals: Gong, Rui, He, Yuan, Liu, Xiao-Yun, Wang, Hai-Yun, Sun, Li-Yue, Yang, Xin-Hua, Li, Bin, Cao, Xin-Kai, Ye, Zu-Lu, Kong, Ling-Heng, Zhang, Da-Dong, Li, Yu-Hong, Xu, Rui-Hua, Shao, Jian-Yong
Format: Artigo
Idioma:Inglês
Publicat: Dove 2019
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500872/
https://ncbi.nlm.nih.gov/pubmed/31118792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S193985
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