Mutation spectrum of germline cancer susceptibility genes among unselected Chinese colorectal cancer patients

Background: Genetic factors play an important role in colorectal cancer (CRC) risk, yet the prevalence and spectrum of germline cancer susceptibility gene mutations among unselected Chinese CRC patients is largely undetermined. Methods: We performed next-generation sequencing with a 73-genes panel a...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Gong, Rui, He, Yuan, Liu, Xiao-Yun, Wang, Hai-Yun, Sun, Li-Yue, Yang, Xin-Hua, Li, Bin, Cao, Xin-Kai, Ye, Zu-Lu, Kong, Ling-Heng, Zhang, Da-Dong, Li, Yu-Hong, Xu, Rui-Hua, Shao, Jian-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500872/
https://ncbi.nlm.nih.gov/pubmed/31118792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S193985
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