AS03-Adjuvanted H5N1 Avian Influenza Vaccine Modulates Early Innate Immune Signatures in Human Peripheral Blood Mononuclear Cells

BACKGROUND: Adjuvant System 03 (AS03) markedly enhances responses to influenza A/H5N1 vaccines, but the mechanisms of this enhancement are incompletely understood. METHODS: Using ribonucleic acid sequencing on peripheral blood mononuclear cells (PBMCs) from AS03-adjuvanted and unadjuvanted inactivat...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Howard, Leigh M, Goll, Johannes B, Jensen, Travis L, Hoek, Kristen L, Prasad, Nripesh, Gelber, Casey E, Levy, Shawn E, Joyce, Sebastian, Link, Andrew J, Creech, C Buddy, Edwards, Kathryn M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500554/
https://ncbi.nlm.nih.gov/pubmed/30566602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy721
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