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Antimycin A-induced mitochondrial dysfunction activates vagal sensory neurons via ROS-dependent activation of TRPA1 and ROS-independent activation of TRPV1

Inflammation causes activation of nociceptive sensory nerves, resulting in debilitating sensations and reflexes. Inflammation also induces mitochondrial dysfunction through multiple mechanisms. Sensory nerve terminals are densely packed with mitochondria, suggesting that mitochondrial signaling may...

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Detalhes bibliográficos
Publicado no:Brain Res
Main Authors: Stanford, Katherine R, Hadley, Stephen H, Barannikov, Ivan, Ajmo, Joanne M, Bahia, Parmvir K, Taylor-Clark, Thomas E
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500470/
https://ncbi.nlm.nih.gov/pubmed/30914247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2019.03.029
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