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Cellular senescence in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis

Cellular senescence is a form of adaptive cellular physiology associated with aging. Cellular senescence causes a proinflammatory cellular phenotype that impairs tissue regeneration, has been linked to stress, and is implicated in several human neurodegenerative diseases. We had previously determine...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Nicaise, Alexandra M., Wagstaff, Laura J., Willis, Cory M., Paisie, Carolyn, Chandok, Harshpreet, Robson, Paul, Fossati, Valentina, Williams, Anna, Crocker, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500153/
https://ncbi.nlm.nih.gov/pubmed/30910981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1818348116
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