Insertion of a chimeric retrotransposon sequence in mouse Axin1 locus causes metastable kinky tail phenotype

BACKGROUND: Transposable elements (TEs) make up > 50% of the human genome, and the majority of retrotransposon insertions are truncated and many are located in introns. However, the effects of retrotransposition on the host genes remain incompletely known. RESULTS: We report here that insertion o...

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Veröffentlicht in:Mob DNA
Hauptverfasser: Wang, Zhuqing, McSwiggin, Hayden, Newkirk, Simon J., Wang, Yue, Oliver, Daniel, Tang, Chong, Lee, Sandy, Wang, Shawn, Yuan, Shuiqiao, Zheng, Huili, Ye, Ping, An, Wenfeng, Yan, Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500023/
https://ncbi.nlm.nih.gov/pubmed/31073336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13100-019-0162-7
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