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Antibodies and venom peptides: New therapeutic modalities for ion channels

Ion channels play fundamental roles in both excitable and non-excitable tissues and therefore constitute attractive drug targets for a myriad of neurological, cardiovascular and metabolic diseases as well as for cancer and immunomodulation. However, achieving selectivity for specific ion channel sub...

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Bibliographische Detailangaben
Veröffentlicht in:Nat Rev Drug Discov
Hauptverfasser: Wulff, Heike, Christophersen, Palle, Colussi, Paul, Chandy, K. George, Yarov-Yarovoy, Vladimir
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499689/
https://ncbi.nlm.nih.gov/pubmed/30728472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41573-019-0013-8
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